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Diabetes mellitus (DM)

is a major public health problem worldwide. Current global estimates indicate that this condition affects 415 million people and is set to escalate to 642 million by the year 2040.

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Causes

know the cuases of diabetes one and two

Overweight, obesity, and physical inactivity

if you are not physically active and are overweight or obese. Extra weight sometimes causes insulin resistance and is common in people with type 2 diabetes.

Insulin resistance

Type 2 diabetes usually begins with insulin resistance, a condition in which muscle, liver, and fat cells do not use insulin well. As a result, your body needs more insulin to help glucose enter cells.

Genes and family history

As in type 1 diabetes, certain genes may make you more likely to develop type 2 diabetes. Genes also can increase the risk of type 2 diabetes by increasing a person’s tendency to become overweight or obese.

Genetic mutations

Monogenic diabetes is caused by mutations, or changes, in a single gene. These changes are usually passed through families, but sometimes the gene mutation happens on its own.

Hormonal diseases

Some hormonal diseases cause the body to produce too much of certain hormones, which sometimes cause insulin resistance and diabetes.

Damage to or removal of the pancreas

Pancreatitis, pancreatic cancer, and trauma can all harm the beta cells or make them less able to produce insulin, resulting in diabetes.

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symptoms

Symptoms of diabetes include

increased thirst and urination

Your kidneys are forced to work overtime to filter and absorb the excess glucose.

increased hunger

In uncontrolled diabetes where blood glucose levels remain abnormally high ( hyperglycemia ),

numbness or tingling in the feet or hands

Diabetic neuropathy most often damages nerves in the legs and feet.

sores that do not heal

Uncontrolled diabetes may also affect circulation, causing blood to move more slowly

unexplained weight loss

When the glucose doesn't arrive in your cells, your body thinks it's starving and finds a way to compensate.

fatigue

Fatigue and weakness might result when the cells do not get enough glucose.